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Search Results for " cyclosporine a "

6

Compounds

Cat No. Product Name Synonyms Targets
T0945 Cyclosporin A Cyclosporine A,Ciclosporin,Cyclosporine Phosphatase , Antibiotic , Complement System
Cyclosporin A is a naturally occurring cyclic polypeptide that is the active metabolite of a fungus. Cyclosporin A is an immunosuppressant that binds to procyclins and inhibits calcineurin (IC50=7 nM).
T6459 Cyclosporine Phosphatase
Cyclosporine is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation.
T9936 ZX-J-19J N-(2,3-Diphenyl-6-quinoxalinyl)octanamide Others
ZX-J-19J (N-(2,3-Diphenyl-6-quinoxalinyl)octanamide), an inhibitor of Cyclophilin J (CyPJ), demonstrates remarkable inhibition of tumor cell growth, comparable to cyclosporine A but much stronger than 5-fluorouracil.
T70889 Oxeclosporin
Oxeclosporin is a hydroxyethyl derivative of serine(8)-cyclosporine; inhibits proliferation and functions of lymphocytes.
T32020 Gusperimus Deoxyspergualin,15-Deoxyspergualin
Gusperimus was synthesized by chemical modification of spergualin and in combination with cyclosporine A to prevent diabetes in susceptible NOD mice.
T34999 UNIL-088 UNIL 088
UNIL088 is a water-soluble prodrug of cyclosporine A (CsA) designed for topical ocular delivery. The pro-moiety is grafted via an ester function to CsA and the solubilizing group is a phosphate ion. UNIL-088 can be rapid...
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